After this post [thank you all, for your thoughts] I thought I should give you the latest update with Murdock.
Friday Adam took Murdock to the vet [I was at my emotional end with spending 1/2 days at the vet, waiting & not getting any answers].
He is still on three of these medications, but one of them is specifically hard on large breed dogs. Other than increased appetite & urination, it causes diabetes, & is thinning his skin. So, we are trying to wean him off that medication again [we tired once & his nodules came right back]. If that is successful, we'll take him off a second medication. If not, our only other option is to try a [human] cancer drug. The negative thing about that option...we would need to take him back to Ames for check ups [blood/urine draw] every 2 weeks [read::extremely time sucking & ridiculously expensive considering each time we go-currently every 3 weeks-it's $150-200]
On a positive note, he gained 5 pounds [even though he's lost most all of his muscle & it's all fat weight]
So...we wait & see how he reacts to the decreased dosage of prednisone.